Methotrexate as a Suspected Trigger of Macrophage Activation Syndrome in Juvenile Idiopathic Arthritis

Authors

  • Soumya Roy Institute Of Child Health, Kolkata
  • Subroto Chakrabartty Institute Of Child Health, Kolkata

Keywords:

Macrophage activation syndrome, Methotrexate, Systemic Onset Juvenile Idiopathic Arthritis

Abstract

A four year old girl with systemic onset juvenile idiopathic arthritis (SOJIA) developed macrophage activation syndrome (MAS) shortly after starting methotrexate. We observed methotrexate is a likely trigger of MAS in SOJIA. Possibly, there are only two case reports suggesting methotrexate triggered MAS. We reviewed the literature for possible mechanisms.

Author Biographies

Soumya Roy, Institute Of Child Health, Kolkata

Post graduate trainee and junior resident,, Dept Of Paediatrics 

Subroto Chakrabartty, Institute Of Child Health, Kolkata

Professor Of Paediatrics

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Published

2017-10-04

Issue

Vol. 37 No. 1 (2017)

Section

Case Reports